Description

Colchicum-Dispert (Colchicine 0.5 mg. | 25 tabs.)

How to use Colchicine 0.5 Mg Tablet

Read the Patient Information Leaflet if available from your pharmacist before you start taking colchicine and each time you get a refill. If you have any questions, ask your doctor or pharmacist.
To reduce the risk of serious heart disease, take this medication by mouth with or without food as directed by your doctor, usually once daily.
If you are using the extended-release tablets, swallow the tablets whole. Do not crush or chew the tablets. Doing so can release all of the drug at once, increasing the risk of side effects.
Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day.

Side Effects

Diarrhoea, nausea, cramping, abdominal pain, and vomiting may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.
Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Tell your doctor right away if you have any serious side effects, including: fast heartbeat, shortness of breath, signs of infection (such as sore throat that doesn’t go away, fever, chills), signs of kidney problems (such as change in the amount of urine), unusual bleeding/bruising, unusual weakness/tiredness.
Stop taking this medication and get medical help right away if you have any very serious side effects, including: muscle weakness or pain, numbness/tingling in your fingers or toes, pale or grey colour of the lips/tongue/palms of hands.
A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

Precautions

Before taking colchicine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: bleeding/blood problems, kidney problems, liver problems.
This medication can affect how well your body absorbs some foods and nutrients (such as vitamin B12). Consult your doctor or pharmacist for more details.
Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).
Older adults may be more sensitive to the side effects of this drug, especially muscle weakness/pain and numbness/tingling in their fingers or toes.

Interactions

See also How to Use and Precautions sections.
Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor’s approval.
Other medications can affect the removal of colchicine from your body, which may affect how colchicine works or increase the risk of serious side effects. Examples include adagrasib, certain azole antifungals (such as itraconazole, ketoconazole), diltiazem, HIV protease inhibitors (such as atazanavir, darunavir), macrolide antibiotics (such as clarithromycin, erythromycin), ritonavir, telithromycin, tucatinib, verapamil, among others.
Colchicine may rarely cause a certain kind of serious (even fatal) muscle damage (rhabdomyolysis). This muscle damage releases substances that can lead to serious kidney problems. The risk may be increased if other drugs that may also cause rhabdomyolysis are taken along with colchicine. Some affected drugs include: atorvastatin, digoxin, gemfibrozil, pravastatin, simvastatin, among others.
This medication may interfere with certain lab tests, possibly causing false test results. Make sure lab personnel and all your doctors know you use this drug.

Overdose

If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call or visit medical services. Symptoms of overdose may include: severe nausea/vomiting/diarrhea, abdominal pain, trouble breathing, weakness.